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Product
Citations |
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Apoptosis
Detection Kits (Apo Logix FAM-FMK) Citations |
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Granzyme
B activates procaspase-3 which signals a mitochondrial amplification
loop for maximal apoptosis - Sunil
S. Metkar, Baikun Wang, Michelle L. Ebbs,Jin H. Kim,Yong J. Lee,
Srikumar M. Raja, Christopher J. Froelich - Journal of Cell Biology,
Volume 160, Number 6, 875-885, 2003
Small-molecule
XIAP inhibitors derepress downstream effector caspases
and induce apoptosis of myeloid Leukemia cells
- Carter, Gronda, Wang, et.al - Blood, May2005, Vol 105, No 10,
pp4043-4050
Fenretinide
enhances rituximab-induced cytotoxicity against B-cell lymphoma
xenografts through a caspase dependant mechanism -
Gopal, Pagel, et.al - Blood, May 2004, Vol 103, No 9, pp 3516-3520.
http://www.nature.com/leu/journal/v19/n1/full/2403560a.html
Anoxia
Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment
- Papandreou, Krishna, Kaper, et.al - Cancer Research 65, 3171-3178,
April 15, 2005
Thimerosal
induces DNA Breaks,
Caspase 3 Activation, Membrane Damage and Cell Death in Cultured Human
Neurons and Fibroblasts -
Baskin, Ngo, Didenko - Toxicological Sciences 74, 2003
IFN- Induces
Apoptosis in Ovarian Cancer Cells
in Vivo and in Vitro - Wall,
Burke, Barton, Smyth, Balkwill - Clinical Cancer Research Vol. 9,
2487-2496, July 2003
http://www.nature.com/onc/journal/v24/n24/full/1208542a.html
The
removal of extracellular calcium: a novel mechanism underlying the
recruitment of N-methyl-d-aspartate
(NMDA) receptors in neurotoxicity
- Xin, Zhao, Gang, et.al - European Journal of Neuroscience Vol 21,
Issue 3, pg 622 - Feb 2005
Deficiency
of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes
Apoptosis of Activated/Memory T Cells, and inhibits spontaneous
systemic Autoimmunity - J. Exp
Medicine; Vol 199, Number 4, Feb 16 2004; 547-557
Ligand-independent
redistribution of Fas (CD95) into lipid rafts
mediates clonotypic T cell death
- Jagan R Muppidi & Richard M Siegel - Nature Immunology 5, 182
- 189 (2004)
Attenuation
of apoptosis in enterocytes by blocking potassium channels
- Levitan, Makhina, et. al - Am J Physiol Gastrointest Liver Physiol
(July 14, 2005).
Induction
of Apoptosis Using Inhibitors of Lysophosphatidic Acid
Acyltransferase-ß and Anti-CD20 Monoclonal Antibodies for
Treatment of Human Non-Hodgkin's Lymphomas
- John M. Pagel, Christian Laugen, Lynn Bonham, Robert C. Hackman,
et.al - Clinical Cancer Research Vol. 11, 4857-4866, July 1,
2005.
Inhibition
of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in
B-lineage ALL in the presence of stromal cell support
- Bertrand, Spengeman, Shelton, et.al - Leukemia (2005), 19, 98-102.
Tumor
Suppressor DAL-I/4. IB and protein Methylation cooperate in inducing
apoptosis MCF-7 breast cancer cells
- Molecular Cancer 2006, 5:4
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Antibody
specific Caspase 3 Detection Kit Citations (Apo Active 3) |
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The
endoplasmic reticulum is the site of cholestrol-induced cytotoxicity in
macrophages - Feng, Yao, Li, Devlin et al
- Nature Cell Biology Vol 5, No 9, September 2003, pp 781-792
Deficiency
of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of
Activated/Memory T Cells, and inhibits spontaneous systemic Autoimmunity
- J. Exp Medicine; Vol 199, Number 4, Feb 16 2004; 547-557
Melanin
acts as a potent UVB photosensitizer to cause an atypical mode of cell
death in murine skin - Seiji Takeuchi, Wengeng Zhang, Kazumasa
Wakamatsu, Shosuke
Ito,Vincent J. Hearing, Kenneth H. Kraemer and Douglas E. Brash
- PNAS U S A. 2004 October 19; 101(42): 15076–15081
Enhanced
growth inhibition of squamous cell carcinoma of the head and neck by
combination therapy of paclitaxel and opioid growth factor -
Patricia McLaughlin, Jeffrey Jaglowski, et al -
International Journal of Oncology 26:
809-816, 2005
Maternal
Antibody Responses to the 52-kd SSA/Ro p200 Peptide and the Development
of Fetal Conduction defects - Clancy, Buyon, Ikeda, et.al -
Arthritis and Rheumatism Vol 52, No 10, October 2005, pp 3079-3086
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Mitochondria
Membrane Potential Detection Kit Citations (JC1) |
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http://www.oldcitypublishing.com/FullText/JETOfulltext/JETO4.2fulltext/Yount.pdf
Deficiency
of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of
Activated/Memory T Cells, and inhibits spontaneous systemic Autoimmunity
- J. Exp Medicine; Vol 199, Number 4, Feb 16 2004; 547-557
Defects
in Cell Growth Regulation by C18:0-Ceramide
and Longevity Assurance Gene 1
(LAG1) in Human Head and Neck Squamous Cell Carcinomas (HNSCC) - Serap
Koybasi, Can E. Senkal, Kamala Sundararaj, et al. - JBC Papers in Press. Published on
August 17,
2004 as Manuscript M406920200
Tocotrienol-induced
cytotoxicity is unrelated tomitochondrial stress apoptotic signaling in
neoplastic mammary epithelial cells - Sumit J. Shah and
Paul W. Sylvester - Biochem.
Cell Biol. Vol. 83, 2005
β
Adrenergic
receptor-stimulated apoptosis in adult cardiac myocytes involves
MMP-2-mediated disruption of β1
integrin signaling and mitochondrial pathway - Bindu Menon,Mahipal
Singh, Robert Ross, Jennifer N. Johnson and Krishna Singh -
Am J
Physiol Cell
Physiol 290: C254-C261, 2006. First published September 7, 2005
SGLT-1-mediated
glucose uptake protects intestinal epithelial cells against LPS-induced
apoptosis and barrier defects: a novel cellular rescue mechanism? -
Linda C. H. Yu Andrew N. Flynn, Jerrold R. Turner and Andre G. Buret-
The FASEB Journal. 2005;19:1822-1835
Ceramide
induces mitochondrial abnormalities in insulin-secreting INS-1 cells:
Potential mechanisms underlying ceramide-mediated metabolic dysfunction
of the β cell -
R. Veluthakal, R. Palanivel Y. Zhao,
P. McDonald, S. Gruber and A. Kowluru -
Apoptosis Journal, Vol 10/No 4, Aug 2005
Opposing
effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated
apoptosis - Yun Liu,
Zhiguo Liu, Hua Gao, You Zhou, Elliot
J Androphy and Jason J Chen - Oncogene (March 2005)
24, 3942–3953
Increased
Stress-Induced Generation of Reactive Oxygen Species and Apoptosis in
Human Keratoconus Fibroblasts -
Marilyn Chwa, Shari R. Atilano, Vinitha Reddy, et.al - Investigative
Ophthalmology and Visual Science. 2006;47:1902-1910
Resveratrol-caused
apoptosis of human prostate carcinoma LNCaP cells is mediated via
modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2
family proteins
-
Moammir
H. Aziz,Minakshi
Nihal, Vivian X. Fu, David F.Jarrard and N Ahmad - Mol Cancer Ther.
2006;5:1335-1341
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Dual
Sensor MitoCasp Citations |
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Caspase
3/7 High Throughout Assay - Apo 3/7 HTS Citations |
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Fluoro
Catalase Detection Kit Citations |
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Expressions of HIF
Prolyl Hydroxlase Isozymes in Growth Plate Chondrocytes: Relationship
between maturation and Apoptotic Sensitivity
- Terkhorn, Bohensky, Shapiro, et. al - Journal of Cellular Physiology
210:257-265 (2007)
3β-Hydroxysteroid- 24
Reductase Is a Hydrogen Peroxide Scavenger, Protecting Cells from
Oxidative
Stress-Induced Apoptosis - Xiuli
Lu, Fukushi
Kambe, Xia
Cao, Yasuko
Kozaki, Takahide
Kaji, Takehisa
Ishii and Hisao
Seo - Endocrinology Vol. 149, No. 7 3267-3273,
2008.
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DNA
Damage
(ApossDNA)
Detection Kit Citations |
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Overexpression
of human truncated peroxisome proliferator-activated receptor 
induces apoptosis in
HL-1 cardiomyocytes -
Cardiovacular
Research 2008 79(3):458-463 - Javier Beaumont Teresa Arias, Susana
Ravassa and Javier Díez
Inhibition
of Src reduces gemcitabine-induced cytotoxicity in human pancreatic
cancer cell lines - Cancer
Letters, Volume 260, Issue 1,
Pages 155-162 - N. Ichihara, Y.
Kubota, A. Kitanaka, T. Tanaka, T.
Taminato
Inhibition
of Eyes Absent Homolog 4 expression induces malignant peripheral nerve
sheath tumor necrosis -
S J Miller , Z D Lan , A Hardiman , J Wu , J J Kordich , D M Patmore ,
R S Hegde , T P Cripe , J A Cancelas , M H Collins & N Ratner -
Oncogene 29, 368–379 (21 January 2010) |
doi:10.1038/onc.2009.360
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Superoxide
Dismutase Detection Kit Citations |
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| |
Expressions of HIF
Prolyl Hydroxlase Isozymes in Growth Plate Chondrocytes: Relationship
between maturation and Apoptotic Sensitivity
- Terkhorn, Bohensky, Shapiro, et. al - Journal of Cellular Physiology
210:257-265 (2007) |
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Fluoro
H2O2
Detection Kit Citations |
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Deficiency
of
the Bax
gene attenuates denervation-induced apoptosis -
P. M. Siu
and S. E. Alway - Apoptosis Journal Vol 11/No 6 June
2006 |
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Fluoro
Thiol
Detection Kit Citations |
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Androgens
Induce Dopaminergic Neurotoxicity via Caspase-3-Dependent Activation of
Protein Kinase Cδ - Rebecca
L.
Cunningham, Andrea Giuffrida, and James L. Roberts - Endocrinology,
doi:10.1210/en.2009-0640 |
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ACT1
Assay
for Cytotoxicity Citations |
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Tetanus
toxoid provides efficient T-cell help
for the induction of HA-1H
cytotoxic T cells - Britta
Eiz-Vesper, Peter A. Horn, Claudia Daubert, Barbara Khattab,
and Rainer Blasczyk -
Transplantation and Cellular Engineering 2006
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Fluoro
NAD/NADH Assay Citations |
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Ethanol
disrupts chondrification of the neurocranial cartilages in medaka
embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1A2) promoter
methylation- Yuhui
Hu, Kristine L. Willett, Ikhlas A.
Khan, Brian E. Scheffler and Asok K. Dasmahapatra - Comparitive
Biochemistry and Physiology Part C: Toxicology & Pharmacology
Vol
150, issue 4, November 2009, pp 495-502 |
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Bioluminescence
Cytotoxicity Assay Citations - aCella-TOX |
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Henry
Ogbomo, Anke Hahn,
Janina Geiler, Martin Michaelis, Hans Wilhelm Doerr, Jindrich Cinatl
Jr. NK sensitivity of Neuroblastoma cells determined by a highly
sensitive coupled luminescent method;Biochemical and Biophysical
Research Comunications 339 (2006) pp375-379.
Click here to read the publication
Resistance
to Cytarabine induces the Up-regulation of NKG2D Ligands and enhances
Natural Killer (NK) cell Lysis of Leukemic Cells
- H Ogbomo, Martin
Michaelis, Denise Klassert, Hans Wilhelm Doerr and Jindrich Cinatl Jr.
- Neoplasia, Vol 10, No 12, pp 1402-1410, Dec 2008
Inhibition
of human
mesenchymal stem cell-derived adipogenesis by the environmental
contaminant benzo(a)pyrene - Normand Podechard,
Olivier Fardel, Michel
Corolleur, Marc Bernard, and Valérie Lecureur - Toxicology
In
Vitro - Vol 23, Issue 5, Aug 2009 - In Press
Tumor
cells infected with oncolytic influenza A virus prime natural killer
cells for lysis of resistant tumor cells -
Henry
Ogbomo, Martin
Michaelis, Janina Geiler, Marijke van Rikxoort,
Thomas Muster, Andrej Egorov, Hans Wilhelm Doerr and Jindrich Cinatl Jr
- Medical Microbiology and Immunology - 15 December 2009
Phase
I
Active Immunotherapy With Combination
of Two Chimeric, Human
Epidermal Growth Factor Receptor 2, B-Cell Epitopes Fused to a
Promiscuous T-Cell Epitope in Patients With Metastatic and/or Recurrent
Solid Tumors - Pravin T.P.
Kaumaya, Kevin Chu Foy, Joan Garrett, Sharad V. Rawale, Daniele Vicari,
Jennifer M. Thurmond, Tammy Lamb, Aruna Mani, Yahaira Kane, Catherine
R. Balint, Donald Chalupa, Gregory A. Otterson, Charles L. Shapiro,
Jeffrey M. Fowler, Michael R. Grever, Tanios S. Bekaii-Saab, William E.
Carson, III - - Journal of Clinical Oncology, Vol 27, No 31 (November
1), 2009: pp. 5270-5277
A
novel immunomodulatory mechanism of ribavirin in suppressing natural
killer cell function - Henry
Ogbomo, Martin Michaelis, Behric
Altenbrandt, Hans Wilhelm Doerr, and Jindrich Cinatl Jr -
Biochemical Pharmacology, Vol 79, issue 2, Jan 2010, pp 188-197
Corey, M. J. and Kinders,
R. J. (2005) "Coupled Luminescent Methods in Drug Discovery: 3-Min
Assays for Cytotoxicity
and Phosphatase Activity" Drug Discovery Handbook, Ed. Shayne Cox Gad,
published by John Wiley & Sons, Inc., pp. 689-731
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