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  Product Citations  
  Apoptosis Detection Kits (Apo Logix FAM-FMK) Citations  
  Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis - Sunil S. Metkar, Baikun Wang, Michelle L. Ebbs,Jin H. Kim,Yong J. Lee, Srikumar M. Raja, Christopher J. Froelich - Journal of Cell Biology, Volume 160, Number 6, 875-885, 2003

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of myeloid Leukemia cells - Carter, Gronda, Wang, et.al - Blood, May2005, Vol 105, No 10, pp4043-4050

Fenretinide enhances rituximab-induced cytotoxicity against B-cell lymphoma xenografts through a caspase dependant mechanism - Gopal, Pagel, et.al - Blood, May 2004, Vol 103, No 9, pp 3516-3520.

http://www.nature.com/leu/journal/v19/n1/full/2403560a.html 

Anoxia Is Necessary for Tumor Cell Toxicity Caused by a Low-Oxygen Environment - Papandreou, Krishna, Kaper, et.al - Cancer Research 65, 3171-3178, April 15, 2005


Thimerosal induces DNA Breaks, Caspase 3 Activation, Membrane Damage and Cell Death in Cultured Human Neurons and Fibroblasts - Baskin, Ngo, Didenko - Toxicological Sciences 74, 2003

IFN-{gamma} Induces Apoptosis in Ovarian Cancer Cells in Vivo and in Vitro - Wall, Burke, Barton, Smyth, Balkwill - Clinical Cancer Research Vol. 9, 2487-2496, July 2003

http://www.nature.com/onc/journal/v24/n24/full/1208542a.html

The removal of extracellular calcium: a novel mechanism underlying the recruitment of N-methyl-d-aspartate (NMDA) receptors in neurotoxicity - Xin, Zhao, Gang, et.al - European Journal of Neuroscience Vol 21, Issue 3, pg 622 - Feb 2005

Deficiency of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells, and inhibits spontaneous systemic Autoimmunity - J. Exp Medicine; Vol 199, Number 4, Feb 16 2004; 547-557


Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death - Jagan R Muppidi & Richard M Siegel - Nature Immunology 5, 182 - 189 (2004)

Attenuation of apoptosis in enterocytes by blocking potassium channels - Levitan, Makhina, et. al - Am J Physiol Gastrointest Liver Physiol (July 14, 2005).

Induction of Apoptosis Using Inhibitors of Lysophosphatidic Acid Acyltransferase-ß and Anti-CD20 Monoclonal Antibodies for Treatment of Human Non-Hodgkin's Lymphomas - John M. Pagel, Christian Laugen, Lynn Bonham, Robert C. Hackman, et.al - Clinical Cancer Research Vol. 11, 4857-4866, July 1, 2005. 

Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support - Bertrand, Spengeman, Shelton, et.al - Leukemia (2005), 19, 98-102.

Tumor Suppressor DAL-I/4. IB and protein Methylation cooperate in inducing apoptosis MCF-7 breast cancer cells - Molecular Cancer 2006, 5:4
 
  Antibody specific Caspase 3 Detection Kit Citations (Apo Active 3)  
  The endoplasmic reticulum is the site of cholestrol-induced cytotoxicity in macrophages - Feng, Yao, Li, Devlin et al - Nature Cell Biology Vol 5, No 9, September 2003, pp 781-792

Deficiency of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells, and inhibits spontaneous systemic Autoimmunity - J. Exp Medicine; Vol 199, Number 4, Feb 16 2004; 547-557

Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin - Seiji Takeuchi, Wengeng Zhang, Kazumasa Wakamatsu, Shosuke Ito,Vincent J. Hearing, Kenneth H. Kraemer and Douglas E. Brash - PNAS U S A. 2004 October 19; 101(42): 15076–15081

Enhanced growth inhibition of squamous cell carcinoma of the head and neck by combination therapy of paclitaxel and opioid growth factor - Patricia McLaughlin, Jeffrey Jaglowski, et al - International Journal of Oncology 26: 809-816, 2005

Maternal Antibody Responses to the 52-kd SSA/Ro p200 Peptide and the Development of Fetal Conduction defects - Clancy, Buyon, Ikeda, et.al - Arthritis and Rheumatism Vol 52, No 10, October 2005, pp 3079-3086

 
  Mitochondria Membrane Potential Detection Kit Citations (JC1)  
  http://www.oldcitypublishing.com/FullText/JETOfulltext/JETO4.2fulltext/Yount.pdf

Deficiency of the Cyclin Kinase inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells, and inhibits spontaneous systemic Autoimmunity - J. Exp Medicine; Vol 199, Number 4, Feb 16 2004; 547-557

Defects in Cell Growth Regulation by C18:0-Ceramide and Longevity Assurance Gene 1 (LAG1) in Human Head and Neck Squamous Cell Carcinomas (HNSCC) - Serap Koybasi, Can E. Senkal, Kamala Sundararaj, et al. - JBC Papers in Press. Published on August 17, 2004 as Manuscript M406920200

Tocotrienol-induced cytotoxicity is unrelated tomitochondrial stress apoptotic signaling in neoplastic mammary epithelial cells - Sumit J. Shah and Paul W. Sylvester - Biochem. Cell Biol. Vol. 83, 2005

β Adrenergic receptor-stimulated apoptosis in adult cardiac myocytes involves MMP-2-mediated disruption of β1 integrin signaling and mitochondrial pathway - Bindu Menon,Mahipal Singh, Robert Ross, Jennifer N. Johnson and Krishna Singh -   Am J Physiol Cell Physiol 290: C254-C261, 2006. First published September 7, 2005

SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: a novel cellular rescue mechanism? - Linda C. H. Yu Andrew N. Flynn, Jerrold R. Turner and Andre G. Buret- The FASEB Journal. 2005;19:1822-1835

Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins - Moammir H. Aziz,Minakshi Nihal, Vivian X. Fu, David F.Jarrard and N Ahmad - Mol Cancer Ther. 2006;5:1335-1341 

 
  Dual Sensor MitoCasp Citations  
 
Identification of single-domain, Bax-specific intrabodies that confer resistance to mammalian cells against oxidative-stress-induced apoptosis - Deyzi Gueorguieva, Shenghua Li, Nicole Walsh, Amit Mukerji, Jamshid Tanha, and Siyaram Pandey - The FASEB Journal 2006
 
 
OSU-03012, a Novel celecoxib derivative, Is cytotoxic to Myeloma cells and Acts through Multiple mechanisms - Zhang, Suvannasankha, Crean, White, Johnson, Farag et. al - Clinical Cancer research 13, pp 4750-4758, Aug 15th 2007
 
 
  Caspase 3/7 High Throughout Assay - Apo 3/7 HTS Citations  
 
Identification of single-domain, Bax-specific intrabodies that confer resistance to mammalian cells against oxidative-stress-induced apoptosis - Deyzi Gueorguieva, Shenghua Li, Nicole Walsh, Amit Mukerji, Jamshid Tanha, and Siyaram Pandey - The FASEB Journal 2006
 
 
 
  Fluoro Catalase Detection Kit Citations  
  Expressions of HIF Prolyl Hydroxlase Isozymes in Growth Plate Chondrocytes: Relationship between maturation and Apoptotic Sensitivity - Terkhorn, Bohensky, Shapiro, et. al - Journal of Cellular Physiology 210:257-265 (2007)
  Superoxide Dismutase Detection Kit Citations  
  Expressions of HIF Prolyl Hydroxlase Isozymes in Growth Plate Chondrocytes: Relationship between maturation and Apoptotic Sensitivity - Terkhorn, Bohensky, Shapiro, et. al - Journal of Cellular Physiology 210:257-265 (2007)  
  Fluoro H2O2 Detection Kit Citations  
  Deficiency of the Bax gene attenuates denervation-induced apoptosis - P. M. Siu and S. E. Alway - Apoptosis Journal Vol 11/No 6 June 2006  
  ACT1 Assay for Cytotoxicity Citations  
 

Tetanus toxoid provides efficient T-cell help for the induction of HA-1H cytotoxic T cells - Britta Eiz-Vesper, Peter A. Horn, Claudia Daubert, Barbara Khattab, and Rainer Blasczyk - Transplantation and Cellular Engineering 2006

 
  Bioluminescence Cytotoxicity Assay Citations - aCella-TOX  
  1. Methods and compositions for coupled luminescent assays. United States Patent 6,811,990 Corey and Kinders, issued November 2, 2004.  
  2. "Coupled Luminescent Methods in Drug Discovery: 3-Min Assays for Cytotoxicity and Phosphatase Activity" - Corey, M. J. and Kinders, R. J. (2005), Drug Discovery Handbook, Ed. Shayne Cox Gad, published by John Wiley & Sons, Inc., pp. 689-731  
   3.  NK sensitivity of Neuroblastoma cells determined by a highly sensitive coupled luminescent method - Henry Ogbomo, Anke Hahn, Janina Geiler, Martin Michaelis, Hans Wilhelm Doerr, Jindrich Cinatl Jr. - Biochemical and Biophysical Research Comunications 339 (2006) pp375-379.   
   4.  Histone deactylase inhibitors supress natural killer cell cytolytic activity- Henry Ogbomo, et. al - FEBS Lett 2007.